Polyclonal and monoclonal antibodies are some of the best selling therapies. In this article, we explain this antibody difference: “Immunoglobulins or antibodies are Y-shaped molecules secreted by B cells to neutralize antigens. Mode of antibody production that classifies them as monoclonal (made by identical B cells) or polyclonal (made by different B cells). “”
This means that monoclonal antibodies recognize only one epitope per antigen, whereas polyclonal antibodies have a higher affinity for a particular antigen due to the recognition of multiple epitopes. If you are looking for more detail on polyclonal antibody production visit https://www.bosterbio.com/services/custom-polyclonal-antibody-development-service.
The advantage of using monoclonal to polyclonal antibodies in research is that they are more homogeneous and have higher consistency between batches. However, the production of monoclonal antibodies requires different skills and processes. This can add additional cost and time to creating a batch.
Therefore, whether polyclonal or monoclonal antibodies are required depends on the application, the timing of the particular project, and whether a stable cell line already exists. One of the main advantages of working with a trusted supplier in making these decisions is that customers can benefit from professional knowledge and experience to help make decisions.